Medica RCP |Lonsurf 20/8.19mg | Indications | Side Effects | Composition | Route | all.price

Do You Know

03-05-2023 : 769 Pharmacists work as Medical Representative, of which 39 work as Senior Medical Representative * 02-06-2020 : 216 non Pharmacists work as Medical Representative, and 54 work as Senior Medical Representative * 05-06-2023 : In Lebanon, 88 generic medicinal products are more expensive than their Originators * 31-12-2019 : A medicinal product refused in Europe is marketed in Lebanon * 05-06-2023 : At least 332 medicinal products are available on the Lebanese market and are not available in the country of origin * 05-06-2023 : The price of the most expensive medicine available in Lebanon is 30434557 LL * 05-06-2023 : At least 1309 medicinal products are more expensive in Lebanon than in the countries of origin * 01-01-2019 : Daktavira, a generic of Daklinza, is registered in Lebanon but has no public price * 31-12-2019 : 352 medicinal products have been declared as non-marketed or withdrawn * 09-11-2021 : 64.72% of lebanese pharmacists are female * 31-12-2019 : 486 medicines were submitted to the Ministry of Health for a marketing authorization, and 514 medicines were registered to date * 15-06-2018 : The Minister of Public Health, has decided to suspend the commercialization of AB Slim (Ab Care Medical Herbs), which contains sibutramine, sildenafil and phenolphthalein * 01-06-2020 : Some Non-Marketed medicines are still imported * 01-06-2020 : Ixempra, a medicinal product withdrawn in Europe is imported to lebanon * 01-06-2020 : A vaccine made in India, removed from WHO list of prequalified vaccines, is submitted for registration in Lebanon * 01-06-2020 : Lebanon has 14 CROs, and is ranked as one of the largest countries in the world in clinical studies. According to the WHO, 817 clinical studies are currently conducted in Lebanon. * 05-01-2021 : * 01-10-2023 : Adakveo is now withdrawn from use in the European Union due to lack of therapeutic efficacy *

Products » Items » Lonsurf 20/8.19mg

Contraindicated
Congenital malformations

Contraindicated

Lonsurf 20/8.19mg :
Type	Medicine Authorised
Originator	B
Agent	Khalil Fattal & Fils
Distributor	Khalil Fattal & Fils
Laboratory	Servier
Responsible Party	Les Laboratoires Servier
Origin	France
Manufacturer	Les Laboratoires Servier Industrie
Origin	France
ATC	L01BC59

Lonsurf 20/8.19mg :

Oral

Lonsurf 20/8.19mg :

L Antineoplastic and immunomodulating agents

L01 Antineoplastic agents

L01B Antimetabolites

L01BC Pyrimidine analogues

L01BC59 Trifluridine, combinations

Lonsurf 20/8.19mg :

Tipiracil : 8.19mg

Trifluridine (trifluorothymidine) : 20mg

Lonsurf 20/8.19mg :

Adults : Metastatic colorectal cancer 35mg/m²

Lonsurf 20/8.19mg :

Hypromellose (Hydroxypropylmethyl cellulose) (HPMC) (E464)

Lactose monohydrate

Magnesium stearate (E470b)

PEG-8000 (Polyethylene glycol 8000) Macrogol 8000

Starch pregelatinized

Stearic acid (E570) Thickeners and Stabilizers

Titanium dioxide (E171) (CI 77891)

* Excipient with known effect

Hazard Level
◼ Major
◼ Moderate
◼ Minor
◼ Safe

Lonsurf 20/8.19mg :

Revision Date : 01/04/2016

Frequency	Percentage
Very Common	≥ 1/10
Common	≥ 1/100 - < 1/10
Uncommon	≥ 1/1,000 - < 1/100
Rare	≥ 1/10,000 - < 1/1,000
Very Rare	< 1/10,000
Unknown	Cannot be Estimated

Effect	Frequency
Abdominal distension	Uncommon
Abdominal pain	Common
Acne	Uncommon
Activated partial thromboplastin time prolonged	Uncommon
Alopecia	Common
Anaemia	Very Common
Anal inflammation	Uncommon
Angina pectoris	Uncommon
Anxiety	Uncommon
Arrhythmia	Uncommon
Arthralgia (Pain joint) (Joint ache)	Uncommon
Ascites	Uncommon
Bacterial infection	Uncommon
Biliary dilatation	Uncommon
Biliary tract infection	Uncommon
Blister	Uncommon
Blood alkaline phosphatase increased	Common
Blood creatinine increased	Uncommon
Blood lactate dehydrogenase abnormal	Uncommon
Blood urea increased	Uncommon
Bone pain	Uncommon
Breath odour	Uncommon
Buccal polyp	Uncommon
Burning sensation	Uncommon
C-reactive protein increased	Uncommon
Cancer pain	Uncommon
Candidiasis (Candida infection)	Uncommon
Cataract	Uncommon
Colitis	Uncommon
Conjunctivitis	Uncommon
Constipation	Common
Cough	Common
Cystitis noninfective	Uncommon
Decreased appetite	Very Common
Dehydration	Uncommon
Diarrhoea (Diarrhea)	Very Common
Diplopia	Uncommon
Dizziness	Common
Dry eye	Uncommon
Dry skin	Common
Dysaesthesia	Uncommon
Dysguesia (taste perversion) (Taste abnormality) (Taste disturbance)	Common
Dyspepsia	Uncommon
Dysphonia	Uncommon
Dyspnoea (dyspnea)	Common
Ear discomfort	Uncommon
ECG QT prolonged	Uncommon
Embolism	Uncommon
Enteritis infectious	Uncommon
Enterocolitis haemorrhagic	Uncommon
Epistaxis (Nasal bleeding)	Uncommon
Erythema	Uncommon
Erythropenia	Uncommon
Fatigue	Very Common
Febrile neutropenia (Neutropenic fever)	Common
Feeling of body temperature change	Uncommon
Flatulence	Uncommon
Flushing	Common
Gastritis	Uncommon
Gastroduodenal haemorrhage	Uncommon
Gastrooesophageal reflux disease	Uncommon
General physical health deterioration	Uncommon
Gingival bleeding (Gingival hemorrhage)	Uncommon
Gingival infection	Uncommon
Glossitis	Uncommon
Gout	Uncommon
Granulocytopenia	Uncommon
Haematocrit decreased	Uncommon
Haematuria (Hematuria)	Uncommon
Hand and foot syndrome (Palmar-plantar erythrodysaesthesia syndrome)	Common
Headache	Common
Hepatic enzyme increased	Common
Hepatotoxicity (liver toxicity)	Uncommon
Herpes zoster	Uncommon
Hyperaesthesia	Uncommon
Hyperbilirubinaemia	Common
Hyperglycaemia	Uncommon
Hyperhidrosis	Uncommon
Hyperkalaemia	Uncommon
Hypernatraemia	Uncommon
Hypertension	Uncommon
Hypoalbuminaemia	Common
Hypocalcaemia	Uncommon
Hypoesthesia	Uncommon
Hypokalaemia	Uncommon
Hyponatraemia (Hyponatremia)	Uncommon
Hypophosphataemia	Uncommon
Hypotension	Uncommon
Ileus	Uncommon
Impaired gastric emptying	Uncommon
Infection	Uncommon
Influenza	Uncommon
INR increased	Uncommon
Insomnia	Common
Joint swelling	Uncommon
Lethargy	Uncommon
Leucopenia (Leukopenia)	Very Common
Leukocytosis	Uncommon
Leukocyturia	Uncommon
Lower respiratory tract infection	Common
Lung infection	Uncommon
Lymphopenia	Common
Malaise	Common
Menstrual disorder	Uncommon
Micturition disorder	Uncommon
Monocytopenia	Uncommon
Monocytosis	Common
Mouth ulceration	Uncommon
Mucosal inflammation	Common
Muscle spasms	Uncommon
Muscle weakness	Uncommon
Musculoskeletal pain	Uncommon
Myalgia	Uncommon
Nail disorders	Uncommon
Nausea	Very Common
Neuropathy peripheral	Common
Neurotoxicity	Uncommon
Neutropenia	Very Common
Oedema	Common
Oesophagitis	Uncommon
Oral disorder	Common
Oropharyngeal pain	Uncommon
Pain	Uncommon
Pain in extremity (Pain in limb)	Uncommon
Palpitations	Uncommon
Pancreatitis acute	Uncommon
Pancytopenia	Uncommon
Paraesthesia (paresthesia)	Uncommon
Periodontal disease	Uncommon
Photosensitivity reaction	Uncommon
Pleural effusion	Uncommon
Proctalgia	Uncommon
Proteinuria	Common
Pruritus	Common
Pulmonary embolism	Uncommon
Pyrexia	Common
Reflux gastritis	Uncommon
Renal failure	Uncommon
Retching	Uncommon
Rhinorrhoea	Uncommon
Sensation of heaviness	Uncommon
Septic shock	Uncommon
Serum total protein decreased	Uncommon
Skin exfoliation (Flaking skin)	Uncommon
Skin rash	Common
Stomatitis	Common
Subileus	Uncommon
Syncope	Uncommon
Thrombocytopenia (Thrombopenia)	Very Common
Tinea pedis	Uncommon
Tooth disorder	Uncommon
Upper respiratory tract infection	Common
Urinary tract infection	Uncommon
Urticaria	Uncommon
Vertigo	Uncommon
Vision blurred	Uncommon
Visual acuity reduced	Uncommon
Vomiting	Very Common
Weight decreased (Weight loss)	Common
Xerosis	Uncommon

Lonsurf 20/8.19mg :

Abu Dhabi

Bahrain

Belgium

Cyprus

Czech Republic

Denmark

Egypt

Finland

France

Germany

Greece

Iceland

Ireland

Italy

Jordan

KSA

Lebanon

Norway

Oman

Portugal

Qatar

Spain

Sweden

Switzerland

The Netherlands

UAE

Medicine Authorised

Aceda

Mediterranean Pharmaceutical Company

Accord HealthCare

Medicine Authorised

Capecitabine Biogaran

Commercial and Trading Ressources (CTR)

Biogaran

Medicine Authorised

Capecitabine GP-Pharm

Mediterranean Pharmaceutical Company

GP-Pharm

Medicine Authorised

Capecitabine Neapolis

MedisPharm

Neapolis Pharma

Medicine Authorised

Capecitabine SPC 150mg

Advanced Health Care Services

Sudair

Medicine Authorised

Capecitabine SPC 500mg

Advanced Health Care Services

Sudair

Medicine Authorised

Capeda

Benta Trading Co

Benta Laboratories

Medicine Authorised

Dirogit

Abela Freres

Hikma Pharmaceuticals

Medicine Authorised

Lonsurf 15/6.14mg

Khalil Fattal & Fils

Servier

Medicine Authorised

Stivarga

Droguerie R. Pharaon et Fils

Bayer

TAU

Xeloda 150mg

Omnipharma

Roche

Medicine Authorised

Xeloda 500mg

Omnipharma

Cheplapharm

NB : Products With Same Indication

Coming Very Soon

Different Units By MoH Code

Revision Date : 01/03/2017

Revision Date : 01/02/2016

Lonsurf 20/8.19mg MoH 9051 :

Form Tablet, Film-Coated

Packaging Blisters (Al/Al)

Package Size Box of 20

Strength 20mg/8.19mg

Storage Condition <30°C None

Public Price 1230496 L.L.

Stratum E1

NSSF ✔

Quarantine ✘

Reg. Number 18817/1

Submission date 02/07/2017

Registration Year 19/04/2017

Price Comparison

You have to register to view this info

Note

You have to register to view this info

Note

Prices are provided in Dollar ($)

You have to register to view this info

Visitors Count: 30971257

Form	Tablet, Film-Coated
Packaging	Blisters (Al/Al)
Package Size	Box of 20
Strength	20mg/8.19mg
Storage Condition	<30°C None
Public Price	1230496 L.L.
Stratum	E1
NSSF	✔
Quarantine	✘
Reg. Number	18817/1
Submission date	02/07/2017
Registration Year	19/04/2017